[Genetic Counseling of HBOC and Japanese Organization of HBOC].

Genetic testing, which reveals germline mutations, is extremely important for HBOC patients and their families. The evolution of this field has created a need for accurate cancer genetic counseling and risk assessment. Prevention and early therapy are possible in HBOC. If a patient has BRCA1 or BRCA2 mutations, the at-risk relatives should receive the information through genetic counseling. Genetic counseling provides not only information but also psychological and social support so that the patient or subject can autonomously decide. Clinical practice for the treatment of HBOC needs a multidisciplinary network that includes clinical geneticists, breast cancer surgeons, and ovarian cancer surgeons. Thus, the Japan Society of Human Genetics, Japan Breast Cancer Society, and Japan Society of Obstetrics and Gynecology established a new corporation named Japanese Organization of HBOC(JOHBOC)for a HBOC comprehensive medical care system.