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Elements for Success in Managing Type 2 Diabetes With SGLT-2 Inhibitors: Role of the Kidney in Glucose Homeostasis: Implications for SGLT-2 Inhibition in the Treatment of Type 2 Diabetes Mellitus.

The focus on the kidney as a therapeutic target for the treatment of type 2 diabetes mellitus (T2DM) has led to the development of the sodium-glucose cotransporter-2 (SGLT-2) inhibitors, of which 3 are available in the United States. This article addresses the implications for SGLT-2 inhibition in the treatment of T2DM.

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