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PHB2/prohibitin 2: An inner membrane mitophagy receptor.
Cell Research 2017 March
Mitophagy, the selective autophagic elimination of mitochondria, is a conserved cellular process critical for maintaining normal cellular physiology, and defects in this process are associated with certain pathophysiologies. In a recently published paper, Wei et al. describe their discovery of a hitherto unexplored mechanism of marking mitochondria for degradation.
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