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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Zamamidine D, a Manzamine Alkaloid from an Okinawan Amphimedon sp. Marine Sponge.
Journal of Natural Products 2017 April 29
A new manzamine alkaloid, zamamidine D (1), was isolated from an Okinawan Amphimedon sp. marine sponge. The structure of zamamidine D (1) including the relative configuration was elucidated on the basis of spectroscopic data. Zamamidine D (1) is the first manzamine alkaloid possessing a 2,2'-methylenebistryptamine unit as the aromatic moiety instead of a β-carboline unit. Zamamidine D (1) showed antimicrobial activity against several bacteria and fungi.
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