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Back Cover: Eur. J. Immunol. 2'17.
European Journal of Immunology 2017 Februrary
Our back cover features an immunohistological staining of a splenic B-cell follicle (IgM green, IgD blue and MOMA-1 red) in Rag2(-/-) mice reconstituted with pro-B cells propagated in vitro. The image is taken from von Muenchow et al. (pp. 394-405), who describe the long-term propagation of pro-B cells in stromal cell-free cultures. This novel culture method will allow studying B-cell development in much greater detail and might also have clinical implications.
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