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JOURNAL ARTICLE
A Tale of Division and Polarization in the Mammalian Embryo.
Developmental Cell 2017 Februrary 7
The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.
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