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RESEARCH SUPPORT, N.I.H., EXTRAMURAL
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Importance of Clonal Complex 258 and IncF K2-like Plasmids among a Global Collection of Klebsiella pneumoniae with bla KPC .

Gisele Peirano, Patricia A Bradford, Krystyna M Kazmierczak, Liang Chen, Barry N Kreiswirth, Johann D D Pitout
Antimicrobial Agents and Chemotherapy 2017 April
This study was designed to determine the global distribution of clonal complex (CC) 258 and IncFIIK2-like plasmids with bla KPC among 522 global Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates. CC258 (i.e., ST258 [clades I and II], ST11, ST340, and ST512) and ST147 were statistically associated with IncFIIK2-like KPC-containing plasmids and may possess an epidemiological advantage over isolates that harbored non-IncF KPC-harboring plasmids.

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