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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Troponin T levels associated with genetic variants in NOTCH2 and MTNR1B in women with psychosis.
Psychiatry Research 2017 April
Psychosis patients have increased prevalence of metabolic disorders, which increase the risk for cardiovascular disease. Elevated troponin T level is an early biomarker of cardiovascular damage. We tested for association between troponin T levels and genetic risk variants of elevated blood glucose level in psychosis. Glucose and troponin T levels correlated positively. MTNR1B rs10830963 and NOTCH2 rs10923931 associated with troponin T levels in women, adjusted for glucose levels. These findings may indicate metabolic genetic influences on troponin T levels among women with psychosis.
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