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Research Support, N.I.H., Extramural
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Regulation of antimicrobial resistance by extracytoplasmic function (ECF) sigma factors.

Emily C Woods, Shonna M McBride
Microbes and Infection 2017 April
Extracytoplasmic function (ECF) sigma factors are a subfamily of σ70 sigma factors that activate genes involved in stress-response functions. In many bacteria, ECF sigma factors regulate resistance to antimicrobial compounds. This review will summarize the ECF sigma factors that regulate antimicrobial resistance in model organisms and clinically relevant pathogens.

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