Dineolignans of 3-O-4' diphenyl ether-type from fruits of Magnolia obovata.

Seven dineolignans of the 3-O-4' diphenyl ether-type (obovatalignans C-I, respectively), were isolated from fruits of Magnolia obovata through repeated silica gel (SiO2), octadecyl SiO2, and Sep-Pak chromatographies. Their chemical structures were determined based on various spectroscopic methods including NMR, HR-MS, IR, specific rotation, and CD spectrometry. Especially, compounds 1-5 include the relatively rare 1,4-benzodioxane ring moiety in the molecular structure.