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Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS.

V Pirro, A K Jarmusch, C M Alfaro, E M Hattab, A A Cohen-Gadol, R Graham Cooks
Analyst 2017 January 27
Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

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