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RESEARCH SUPPORT, NON-U.S. GOV'T
Assigning the Algal Source of Dimethylsulfide Using a Selective Lyase Inhibitor.
ACS Chemical Biology 2017 January 21
Atmospheric dimethylsulfide (DMS) is massively produced in the oceans by bacteria, algae, and corals. To enable identification of DMS sources, we developed a potent mechanism-based inhibitor of the algal Alma dimethylsulfoniopropionate lyase family that does not inhibit known bacterial lyases. Its application to coral holobiont indicates that DMS originates from Alma lyase(s). This biochemical profiling may complement meta-genomics and transcriptomics to provide better understanding of the marine sulfur cycle.
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