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Contractility of Right Ventricular Myocardium in Male and Female Rats during Physiological and Pathological Hypertrophy.

Yu L Protsenko, A A Balakin, D A Kuznetsov, A G Kursanov, R V Lisin, E A Mukhlynina, O N Lookin
Bulletin of Experimental Biology and Medicine 2017 January
Sex differences in the morphogenesis and adaptation of the mechanisms controlling myocardium contractility during physiological and pathological hypertrophy of the right ventricle were demonstrated in mature rats. The study revealed sex-dependent effects of physiological and pathological cardiac hypertrophy on the coefficient of variation of the cardiomyocyte diameter, length-dependent control of the contractile force, and the maximum velocity of isotonic shortening.

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