Commentary on Human adult neurogenesis across the ages: An immunohistochemical study.

I have read with great interest the paper entitled "Human adult neurogenesis across the ages: An immunohistochemical study" by Dennis et al [1]. The Authors evaluated cell proliferation and neurogenesis in the subventricular zone (SVZ) and subgranular zone (SGZ) of 23 individuals aged 0.2-59 years, using immunohistochemistry and immunofluorescence. The Authors evidenced a marked decline in neurogenesis in both neurogenic niches in early childhood and that after 3 years of age, microglia were the only proliferating cells found in either niche or in the adjacent parenchyma. This article is protected by copyright. All rights reserved.