Prevalence of Cryptosporidium Carriage and Disease in Children with Primary Immune-Deficiencies Undergoing Hematopoietic Stem Cell Transplant in Northern Europe.

A prospective cohort study of children with primary immunodeficiencies undergoing hematopoietic stem cell transplant (HSCT) in the UK investigated the extent and significance of Cryptosporidium carriage in this high-risk group. Three of 42 children recruited were infected with Cryptosporidium, a lower proportion than previously described. One had serious disease. The underlying immunodeficiency likely had a bearing on the clinical presentation and possible outcome of infection.