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Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Immune Cell Intolerance for Excess Cholesterol.

Scott B Widenmaier, Gökhan S Hotamışlıgil
Immunity 2016 December 21
Chronic metabolic challenges have severe consequences on physiological systems. In this issue of Immunity, Ito et al. (2016) show that defects in cholesterol metabolism in CD11c+ immune cells result in impaired antigen presentation and ultimately in autoimmune disease.

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