Cover Picture: New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites (ChemistryOpen 3/2016).

The Front Cover picture shows new silver (Ag) and gold (Au) nanoparticle-based tetracycline (TC) nanocomposites (AuNPs@TC and AgNPs@TC). A new synthetic methodology for the preparation of water-soluble Au and Ag nanoparticles, using the antibiotic TC as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability, with an average size of 15±5 and 25±10 nm, respectively. Both composites are tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. Moreover, the sensing towards metal ions is also explored by using AuNPs@TC, which is selective and reversible for aluminum(III) in water. More information can be found in the Full Paper by C. Lodeiro, J. Fernández-Lodeiro, and co-workers on page 206 in Issue 3, 2016 (DOI: 10.1002/open.201600016).