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αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy.

Yan Zhou, Chi-Fai Chan, Daniel W J Kwong, Ga-Lai Law, Steven Cobb, Wai-Kwok Wong, Ka-Leung Wong
Chemical Communications : Chem Comm 2017 January 4
We have synthesized a bifunctional erbium-porphyrin tumor imaging and PDT agent (Er-R3) that is capable of killing bladder cancer cells via its selective binding to the integrin αvβ3 isoform overexpressed on the cell membrane.

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