We have located links that may give you full text access.
Assessing Absorption Coefficient of Hemoglobin in the Breast Phantom Using Near-Infrared Spectroscopy.
Iranian Journal of Radiology : a Quarterly Journal Published By the Iranian Radiological Society 2016 October
BACKGROUND: Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis.
OBJECTIVES: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue.
MATERIALS AND METHODS: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2×, 4× concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data.
RESULTS: The absorption coefficients were 0.075 ± 0.026 cm(-1) for oxygenated Hb (normal) in major vessels and 0.141 ± 0.023 cm(-1) at 4× concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099 ± 0.017 cm(-1) for oxygenated Hb (normal) in minor vessels and 0.171 ± 0.005 cm(-1) at 4× concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically.
CONCLUSION: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels.
OBJECTIVES: In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue.
MATERIALS AND METHODS: A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2×, 4× concentrations of oxy- and deoxy-Hb. The absorption coefficients were determined from spectrometer (SM) and powermeter (PM) data.
RESULTS: The absorption coefficients were 0.075 ± 0.026 cm(-1) for oxygenated Hb (normal) in major vessels and 0.141 ± 0.023 cm(-1) at 4× concentration (abnormal) with SM, whereas the breast absorption coefficients were 0.099 ± 0.017 cm(-1) for oxygenated Hb (normal) in minor vessels and 0.171 ± 0.005 cm(-1) at 4× concentrations with SM. A comparison of the data obtained using a SM and a PM was not significant statistically.
CONCLUSION: The study of the absorption coefficient data of different concentrations of Hb in normal and abnormal breasts via the diffusion of near-infrared light is a valuable method and has the potential to aid in early detection of breast abnormalities with SM and PM in major and minor vessels.
Full text links
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app