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Journal Article
BTLA + Dendritic Cells: The Regulatory T Cell Force Awakens.
Immunity 2016 November 16
The role of dendritic cells (DCs) in the induction of antigen-specific tolerance mediated by extrathymic regulatory T (Treg) cells remains incompletely defined. In this issue of Immunity, Jones et al. (2016) show that BTLA+ DEC205+ CD8+ CD11c+ DCs efficiently induce peripheral Treg cells via the engagement of HVEM, a receptor for BTLA.
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