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JOURNAL ARTICLE
An Unexpected Chink in the Transcriptional Armor of Plasmacytoid Dendritic Neoplasms.
Cancer Cell 2016 November 15
In this issue of Cancer Cell, Ceribelli et al. use functional genomic and chemical screening to reveal the existence of a TCF4/BRD4-dependent oncogenic regulatory network in blastic plasmacytoid dendritic cell neoplasm (BPDCN) and demonstrate that BPDCN cells are highly sensitive to therapeutic targeting of this novel dependency.
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