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JOURNAL ARTICLE
Cholesterol: An Achilles' Heel for Glioblastoma?
Cancer Cell 2016 November 15
In this issue of Cancer Cell, Villa et al. report that survival of glioblastoma cells is dependent on uptake of cholesterol. A synthetic agonist of the Liver X receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.
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