Gd 2 O 3 and GH combined with red blood cells to improve the sensitivity of contrast agents for cancer targeting MR imaging.

Herein, we fabricated efficient MR imaging probes by incorporating gadolinium oxide nanoparticles (Gd2 O3 ) and gadolinium hybrid nanoparticles (GH) within RBCs. The Gd2 O3 and GH encapsulated in the RBCs exhibited high relaxation rates and revealed high sensitivity for T1 MR imaging.