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HISTORICAL ARTICLE
JOURNAL ARTICLE
REVIEW
Necrotizing: A historical perspective.
Seminars in Perinatology 2017 Februrary
Necrotizing enterocolitis is a devastating disease afflicting premature infants, though after 50 years of investigation, the pathophysiology remains elusive. This report describes the possible etiologic factors from a historical perspective, and outlines the importance of human milk, intestinal blood flow, and intestinal blood flow changes from a developmental perspective over the last 40-50 years.
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