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Journal Article
Review
Epigenetic biomarkers in colorectal cancer: premises and prospects.
Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals 2018 March
CONTEXT: Colorectal cancer is one of the most common cancers worldwide. Epigenetic alterations play an important role in the pathogenesis of the colorectal cancer.
OBJECTIVE: This review has focused on the most recent investigations, which has suggested potential epigenetic biomarkers in colorectal cancer.
METHODS: Evidences were achieved by searching online medical databases including Google scholar, Pubmed, Scopus and Science Direct.
RESULTS: Extensive studies have indicated that aberrant epigenetic modifications could serve as potential biomarkers for diagnosis, prognosis and prediction of colorectal cancer.
CONCLUSION: Advances in aberrant epigenetic modifications can open new avenues for exploration of reliable and robust biomarkers to improve the management of CRC patients.
OBJECTIVE: This review has focused on the most recent investigations, which has suggested potential epigenetic biomarkers in colorectal cancer.
METHODS: Evidences were achieved by searching online medical databases including Google scholar, Pubmed, Scopus and Science Direct.
RESULTS: Extensive studies have indicated that aberrant epigenetic modifications could serve as potential biomarkers for diagnosis, prognosis and prediction of colorectal cancer.
CONCLUSION: Advances in aberrant epigenetic modifications can open new avenues for exploration of reliable and robust biomarkers to improve the management of CRC patients.
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