Organelle-specific bioprobes based on fluorogens with aggregation-induced emission (AIE) characteristics.

Fang Hu, Bin Liu

Organic & Biomolecular Chemistry 2016 October 26

Bioprobes based on fluorogens with aggregation-induced emission (AIE) characteristics have been increasingly used in chemosensing and bioimaging due to their high sensitivity, photostability and biocompatibility. In this review, we summarize the design of cellular organelle specific (cytoplasm membrane, mitochondria, lysosomes, lipid droplets and nucleus) AIE bioprobes and their applications in organelle imaging, organelle bioactivity monitoring, and image-guided cancer cell ablation.

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