SP 05-4 IMPLICATIONS OF THE SPRINT TRIAL: ASIAN PERSPECTIVE.

SPRINT is one of the landmark studies, demonstrating that extensive blood pressure (BP) control (BP < 120 mmHg) is superior to standard control (BP < 140 mmHg) in preventing cardiovascular event (CVE). Subjects recruited were older than 50 years without diabetes and had increased risk of CVE. Heart failure, death from cardiovascular cause and death from any cause were major endpoints reduced by extensive BP control. In subgroup analysis, whole spectrum of patients were benefitted. Contrary to several previous studies, this study provides strong evidence for the beneficial effect of extensive BP reduction. However, we need to cautious to apply the results of SPRINT for our daily practice in Asian population. I will discuss several common and different aspects that should be taken in account when applying the results of SPRINT to our daily practice in Asian population.