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JOURNAL ARTICLE
REVIEW
SYSTEMATIC REVIEW
Bariatric manipulation of gastric arteries: A systematic review on the potential concept for treatment of obesity.
International Journal of Surgery 2016 December
BACKGROUND: Gastric artery embolization (GAE) has recently received attention as a minimally invasive intervention in bariatric setting.
AIMS: The current systematic review aimed to gather and categorizes the existing data in the literature regarding bariatric gastric artery manipulation. This will highlight the importance of this potential concept as a therapeutic modality.
METHODS: A PubMed/Medline search was conducted to identify animal and human studies investigating the effect of gastric artery manipulation on weight, ghrelin, obesity, and tissue adiposity.
RESULTS: A total of 9 studies including 6 animal experiments with 71 subjects and 3 human studies with a total of 25 patients were retrieved. Animal subjects underwent chemical embolization while particle embolization was only used in human subjects. Five animal studies and 1 human study reported decreased ghrelin concentration. Three animal experiments and 2 human studies showed a significant weight change following GAE. There was no report regarding a serious adverse event requiring surgical or interventional management.
CONCLUSION: Currently, data regarding the potential role of gastric artery manipulation in decreasing the ghrelin and potential weight loss is scarce.
AIMS: The current systematic review aimed to gather and categorizes the existing data in the literature regarding bariatric gastric artery manipulation. This will highlight the importance of this potential concept as a therapeutic modality.
METHODS: A PubMed/Medline search was conducted to identify animal and human studies investigating the effect of gastric artery manipulation on weight, ghrelin, obesity, and tissue adiposity.
RESULTS: A total of 9 studies including 6 animal experiments with 71 subjects and 3 human studies with a total of 25 patients were retrieved. Animal subjects underwent chemical embolization while particle embolization was only used in human subjects. Five animal studies and 1 human study reported decreased ghrelin concentration. Three animal experiments and 2 human studies showed a significant weight change following GAE. There was no report regarding a serious adverse event requiring surgical or interventional management.
CONCLUSION: Currently, data regarding the potential role of gastric artery manipulation in decreasing the ghrelin and potential weight loss is scarce.
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