Journal Article
Meta-Analysis
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A meta-analysis of contrast-enhanced computer tomography in the diagnosis of colorectal cancer.

OBJECTIVE: To investigate the diagnostic value of contrast-enhanced computer tomography in diagnosis of colorectal cancer.

METHODS: All the diagnostic studies about contrast-enhanced computer tomography in diagnosis of colorectal cancer were searched in the PubMed, Medline, EMBASE, CNKI, and Wanfang databases and included in this meta-analysis. The diagnostic sensitivity and specificity were pooled. The data were analyzed by statistic software Meta-DiSc1.4.

RESULTS: After searching the databases, eight studies with 4764 cases were finally included in this meta-analysis. The combined results showed the pooled diagnostic sensitivity and specificity were 0.73 (95% confidence interval [CI] of 0.69-0.76) and 0.86 (95% CI of 0.85-0.87). Moreover, the area under the receiver operating characteristic was 0.896.

CONCLUSION: Contrast-enhanced computer tomography was a good method for detection colorectal cancer.

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