JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
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Cold Dialysis Solution for Hemodialysis Patients With Fatigue: a Cross-over Study.

INTRODUCTION: The purpose of this study was to explore the effect of cold dialysis on fatigue in hemodialysis patients.

MATERIALS AND METHODS: In a double-blinded cross-over clinical trial, 46 participants were recruited from a hemodialysis unit in Iran. The participants were allocated into 2 groups through simple random sampling method. Each group received 3 sessions of hemodialysis with a dialysis solution temperature of either 37°C 3 or 35.5°C during the first week and then with for another week with the other temperature.  The self-report Piper Fatigue Scale questionnaire was filled out by the participants.

RESULTS: The Piper Fatigue Scale scores in the cold dialysis groups were significantly lower than those in the conventional dialysis solution temperature (P < .001). Reducing the temperature of hemodialysis solution brought a 31.3% reduction in the fatigue score.

CONCLUSIONS: Cold dialysis can be used for all hemodialysis patients as a routine intervention, and in particular, it is recommended dialysis patients who have severe fatigue as a convenient and inexpensive therapeutic option.

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