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Two Cases of Retinoblastoma Invading the Optic Nerve Sheath.
Journal of Pediatric Ophthalmology and Strabismus 2016 September 25
The authors report two cases of retinoblastoma with extension along the optic nerve sheath with negative surgical margins, a pattern not considered in current classifications but suggesting a high risk of metastasis. Both patients were treated with adjuvant chemotherapy alone and remain free of extraocular disease 15 and 22 months later. [J Pediatr Ophthalmol Strabismus. 2016;53:e51-e53.].
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