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Bringing Blood-Based Molecular Testing to the Clinic.

Filip Janku, Razelle Kurzrock
Clinical Cancer Research 2016 November 16
In cancer, plasma-derived cell-free DNA can be used for detection of oncogenic aberrations relevant for treatment selection. A cell-free DNA-based test for EGFR mutations has been approved as an alternative to tumor tissue analysis in lung cancer. Testing for other aberrations, including copy number alterations, continues to be investigated. Clin Cancer Res; 22(22); 5400-2. ©2016 AACRSee related article by Chicard et al., p. 5564.

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