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Journal Article
Research Support, Non-U.S. Gov't
Shedding light on paraspeckle structure by super-resolution microscopy.
Journal of Cell Biology 2016 September 27
The nuclear body paraspeckle is built on the lncRNA Neat1 and plays important roles in gene regulation. In this issue, West et al. (2016. J. Cell Biol https://dx.doi.org/10.1083/jcb.201601071) use super-resolution structured illumination microscopy to show that paraspeckles are organized in a core-shell spheroidal structure composed of Neat1 and seven proteins.
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