OS 14-03 CARDIOVASCULAR RISK MARKERS IN KOREAN ETHNICITY MIGRANTS OF 2-3RD GENERATION LIVING IN SAKHALIN REGION.

OBJECTIVE: In conditions of existing immigration flows, the special relevance has researches concerning cardiovascular risk stratification among of different ethnic origin patients living outside the traditional habitats.

DESIGN AND METHOD: 180 residents of Sakhalin region with arterial hypertension (AG) I-III degree, I-II stage, 88 Korean ethnicity patients, migrants of 2-3-rd generation, 92 Slavic ethnicity patients (58,2 ± 0,93 years old) were examined. The common risk factors and left ventricle (LV) structural-functional characteristics (Echocardiograph Aсuson X-300 HP, USA) were analyzed.

RESULTS: The body mass index (BMI) in Slavic ethnicity patients with AG was significantly different from Korean ethnicity patients (32,7 ± 0,81 кg/м2 and 28,1 ± 0,72, р < 0,001). The Slavic ethnicity patients had more higher waist circumference (WC): 107,31 ± 1,27 and 98,18 ± 1,98 cm; р < 0,001. In 81% of Korean ethnicity patients and 90% of Slavic ethnicity patients were observed atherogenic dyslipidemia. Compared with the Slavs patients, in South-Asian origins had significantly lower high-density lipoprotein level (1,02 ± 0,04 and 1,15 ± 0,03 mmol/l; р < 0,05) and more higher triglycerides level - 2,12 ± 0,05 and 1,91 ± 0,03 mmol/l (р < 0,05). LV wall thickness, LV myocardial mass, LV myocardial mass index and wall relative thickness were higher among the Slavic patients. Statistically significant differences in ethnic groups were obtained in LV end-diastolic and end-systolic dimensions values. There was predominance of concentric LV remodeling in South-Asian origin patients. There was identified positive correlation between LV myocardium mass and BMI, WC in both ethnic groups.

CONCLUSIONS: We described significant differences in individual cardiovascular risk factors among Korean ethnicity patients with AG, migrants of 2-3 generations in comparison with those Slavic ethnicity namely BMI, WC, features of dyslipidemia, LV structural-functional characteristics. Considering to the received data it was an interest to opportunity of development in criteria for an individualized rate of the LV geometry and risk stratification of cardiovascular complications among South-Asian origin patients, migrants of 2-3-rd generations.