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Mechanism and Function of Angiogenin in Apoptosis Regulation.
Zhongguo Sheng Wu Hua Xue Yu Fen Zi Sheng Wu Xue Bao = Chinese Journal of Biochemistry and Molecular Biology 2015 December
Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.
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