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COMPARATIVE STUDY
JOURNAL ARTICLE
T1-weighted MR imaging of glioma at 3T: a comparative study of 3D MPRAGE vs. conventional 2D spin-echo imaging.
Clinical Imaging 2016 November
PURPOSE: This study aims to investigate difference between magnetization-prepared rapid gradient-echo imaging (MPRAGE) and spin-echo (SE) imaging for evaluating glioma on pre-contrast-enhanced (CE) and post-CE T1-weighted images at 3 T.
MATERIALS AND METHODS: We retrospectively assessed pre-CE and post-CE T1-weighted images for tumor contrast in 64 consecutive glioma patients.
RESULTS: In the nonenhancing tumors, the contrast was significantly clearer in MPRAGE than SE. In the enhancing tumors, post-CE contrast ratio was significantly higher in SE than MPRAGE, but when subtraction images are evaluated, the difference got smaller.
CONCLUSION: MPRAGE can be a good substitute of SE for T1-weighted imaging of glioma.
MATERIALS AND METHODS: We retrospectively assessed pre-CE and post-CE T1-weighted images for tumor contrast in 64 consecutive glioma patients.
RESULTS: In the nonenhancing tumors, the contrast was significantly clearer in MPRAGE than SE. In the enhancing tumors, post-CE contrast ratio was significantly higher in SE than MPRAGE, but when subtraction images are evaluated, the difference got smaller.
CONCLUSION: MPRAGE can be a good substitute of SE for T1-weighted imaging of glioma.
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