RYP1 gene as a target for molecular diagnosis of histoplasmosis.

Raimunda Sâmia Nogueira Brilhante, Glaucia Morgana de Melo Guedes, Giovanna Barbosa Riello, Joyce Fonteles Ribeiro, Lucas Pereira Alencar, Silviane Praciano Bandeira, Débora Souza Collares Maia Castelo-Branco, Jonathas Sales Oliveira, Janaína Maria Maia Freire, Jacó Ricarte Lima de Mesquita, Zoilo Pires de Camargo, Rossana de Aguiar Cordeiro, Marcos Fábio Gadelha Rocha, José Júlio Costa Sidrim

Journal of Microbiological Methods 2016 November

This study analyzed the RYP1 gene as a target for the molecular diagnosis of histoplasmosis. This assay detected fungal DNA in 13/13 blood samples from HIV/AIDS-patients with histoplasmosis. Therefore, the detection of RYP1 gene in whole blood sample is a quick and sensitive test to diagnose histoplasmosis.

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