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A new edge to immune surveillance by the neural system.

Jochem H Bernink, Hergen Spits, Wouter J de Jonge
Cell Research 2016 November
A recent paper published in Nature demonstrates a multifaceted relation between enteric glial cells (EGC), intestinal epithelia, and ILC3, via the EGC release of neurotrophic factors, a structurally related group of ligands within the TGF-β superfamily of signaling molecules and IL-22 produced by ILC3.

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