Retrospective characterisation and outcome of canine idiopathic mesenteric purulent lymphadenitis and lymph node abscesses at a teaching hospital from 2005 to 2015.

BACKGROUND: Idiopathic purulent mesenteric lymphadenitis or lymph node abscessation, even though rare in dogs, are important diseases in which rapid diagnosis and treatment is critical. This study aimed to characterise the typical features of these conditions in dogs.

MATERIAL AND METHODS: Archived records from 2005 to 2015 were retrospectively evaluated for the occurrence of idiopathic purulent mesenteric lymphadenitis or lymph node abscesses in dogs. History, physical and clinicopathological abnormalities, diagnostic tests performed, treatment and outcome were reviewed.

RESULTS: A total of 14 cases with histopathologic and/or cytologic confirmation were identified. Typically, there were gastrointestinal signs including abdominal pain and elevated body temperature. Blood analysis revealed non-specific inflammatory changes including elevated C-reactive protein. Half of the bacterial cultures from lymph nodes showed growth of various bacteria. A primary cause was not identified in any case. Out of 14 cases, 10 cases underwent surgery and all dogs were discharged from the hospital. Three suffered from a relapse between 1 and 5 months after discharge but were successfully managed with antibiotics.

CONCLUSION AND CLINICAL RELEVANCE: Idiopathic purulent mesenteric lymphadenitis or lymph node abscessation are infrequent but clinically important diseases. Surgical, symptomatic and antibiotic treatment led to resolution of clinical signs in the evaluated cases. Thorough and standardised diagnostic workup and treatment of future cases are necessary to investigate possible pathogeneses and optimal therapeutic options. Outcome was favourable overall.