We have located links that may give you full text access.
Journal Article
Review
[The effect of antidiabetic treatment on the bone of patients with type 2 diabetes].
Vnitr̆ní Lékar̆ství 0 December
UNLABELLED: Despite a normal or higher bone mass, type 2 diabetes is associated with a higher risk of osteoporotic fractures. Besides a higher falls frequency the lower quality of diabetics bone plays the crucial role in this case. One of the factors affecting their fracture risk is a choice of antidiabetic treatment. So far, professional societies have warned before the thiazolidinediones use only, but gliflozines can be harmful for bone too. Metformin, sulfonylureas, GLP-1 agonists and DPP-4 inhibitors belong to the drugs without a negative effect on the fracture risk. The increased frequency of bone fractures in diabetics treated with insulin lies more in the fact that these patients suffer from diabetes longer, have more diabetic complications and are at a higher risk of hypoglycemia, which is associated with a higher frequency of falls. In individuals with a high fracture risk antidiabetic drugs without a negative effect on bones should be recommended.
KEY WORDS: DPP-4 inhibitors - gliflozines - GLP-1 agonists - insulin - metformin - osteoporosis - sulfonylureas - thiazolidinediones - type 2 diabetes mellitus.
KEY WORDS: DPP-4 inhibitors - gliflozines - GLP-1 agonists - insulin - metformin - osteoporosis - sulfonylureas - thiazolidinediones - type 2 diabetes mellitus.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app