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GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses.

Edward C Lee, Nicholas Davis-Poynter, Chau T H Nguyen, Amelia A Peters, Gregory R Monteith, Ekaterina Strounina, Amirali Popat, Benjamin P Ross
Nanoscale 2016 September 29
A glycosaminoglycan mimetic was attached to the surface of solid and mesoporous silica nanoparticles to create novel antiviral agents against herpes simplex type 1 and type 2 viruses. The nanoparticles act as viral entry inhibitors that appear to block viral attachment and penetration into susceptible cells.

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