[Protein-repellent and antibacterial properties of modified orthodontic adhesive].

OBJECTIVE: To develop a novel protein-repellent orthodontic adhesive by incorporating 2-methacryloyloxyethyl phosphorylcholine(MPC).

METHODS: MPC was incorporated into a commercially available orthodontic adhesive(Fuji ORTHO) at 0% (control), 1.5%, 3.0%, and 5.0% by mass. Enamel shear bond strength(SBS) was determined. Protein adsorption onto specimens was determined by a micro bicinchoninic acid method. A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate biofilm viability.

RESULTS: The SBS was not reduced in the group(3.0% MPC), compared to the control group. The amount of protein adsorption in the group(3.0% MPC) was (0.46±0.06) μg/cm(2) and (4.57 ± 0.42) μg/cm(2) in the control group. Lactic acid production of biofilms in the group(3.0% MPC) was (7.12±1.03) mmol/L and (12.16±1.24) mmol/L in the control group.

CONCLUSIONS: MPC based orthodontic adhesive greatly reduced the protein adsorption and bacterial adhesion, without compromising enamel shear bond strength.