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A Gold(I)-Catalyzed Domino Coupling of Alcohols with Allenes Enables the Synthesis of Highly Substituted Indenes.
Chemistry : a European Journal 2016 October 5
The reaction of aryl-substituted allenes with alcohols under gold catalysis led to highly substituted indenes in good yields, with low catalyst loading and under mild conditions. During this domino transformation, two C-C bonds are formed with water as the only byproduct.
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