CASE REPORTS
JOURNAL ARTICLE
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Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report.

OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation.

CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in peripheral blood smear. The ABO and Rh blood type before the diagnosis of MM was A+, but the following ABO grouping was interpreted as AB+. The ABO genotype revealed the subtypes A102 and O101, which confirmed her ABO phenotype as A+.

CONCLUSION: This was a case of combined group I and III ABO discrepancies mimicking blood group AB.

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