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[Imaging features analysis of Erdheim-Chester].

OBJECTIVE: To investigate the imaging features of Erdheim-Chester.

METHODS: A total of 7 patients with ECD confirmed by pathology were analyzed retrospectively.And the DR(n=5), CT(n=6, 3 patients underwent enhanced scan), MR(n=4, 2 patients underwent enhanced scan) and SPECT (n=3) features were observed.

RESULTS: Among 7 cases of ECD, four cases of DR images showed luffa cystic changes.Five cases of CT images showed bone dissolved, four showed peripheral localized sclerosis, one showed symmetric sclerosis, No enhancement was found on CT scan.Four cases of MR images, three occurred as long T1 and long T2 signal, one occurred as short T1 and long T2 signal, and inhomogeneous enhancement.One case in soft tissue occurred as long T1 and long T2 signal, and inhomogeneous enhancement.Three cases of SPECT images were characterized by radioactive nuclide concentration of diseased region.

CONCLUSION: When ECD lesions located in capitulum and metaphysis, most images of DR and CT show bone dissolved and peripheral localized sclerosis; MRI findings are complicated, the reason might be different proportion of mature and immature lipid components.SPECT would be a kind of effective measure of finding hidden lesion and monitoring curative effect.

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