Psychiatric and Cognitive Effects of Deep Brain Stimulation for Parkinson's Disease.

Adam Nassery, Christina A Palmese, Harini Sarva, Mark Groves, Joan Miravite, Brian Harris Kopell

Current Neurology and Neuroscience Reports 2016 October

Deep brain stimulation (DBS) is effective for Parkinson's disease (PD), dystonia, and essential tremor (ET). While motor benefits are well documented, cognitive and psychiatric side effects from the subthalamic nucleus (STN) and globus pallidus interna (GPi) DBS for PD are increasingly recognized. Underlying disease, medications, microlesions, and post-surgical stimulation likely all contribute to non-motor symptoms (NMS).

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