We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
Review
Spatial integration of E-cadherin adhesion, signalling and the epithelial cytoskeleton.
Current Opinion in Cell Biology 2016 October
The characteristic tall and elongated shape of epithelial cells requires specialized adhesive structures and a distinct organization of cytoskeletal filaments. Cytoskeletal networks coordinate a precise organization of adhesive and signalling complexes along cell-cell contacts and enable exquisite strong cohesion among epithelial cells. E-cadherin, a calcium-dependent adhesion receptor, is an essential adhesive system in epithelia and its dynamic regulation and pathways that stabilize cell-cell adhesion have been extensively studied. This review highlights the less understood mechanisms underlying how cadherin receptor signalling drives cytoskeletal rearrangements which ultimately define the epithelial cell shape. In the past two years, new insights identify specific actin-binding proteins and regulators of the epithelial cytoskeleton as a framework to support junction dynamics, plasticity and maintenance.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app