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CASE REPORTS
JOURNAL ARTICLE
Severe chronic osteomyelitis caused by Morganella morganii with high population diversity.
International Journal of Infectious Diseases : IJID 2016 September
A case of chronic osteomyelitis probably caused by Morganella morganii, occurring over a period of 30 years, is reported. The organism was identified through a combination of sample culture, direct sequencing, and 16S RNA gene amplicon sequencing. Further whole-genome sequencing and population structure analysis of the isolates from the patient showed the bacterial population to be highly diverse. This case provides a valuable example of a long-term infection caused by an opportunistic pathogen, M. morganii, with high diversity, which might evolve during replication within the host.
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