Characteristics and Outcomes of Treatment for Non-ST-Segment Elevation Acute Coronary Syndrome: Results from a Single Center Registry.

BACKGROUND: Acute coronary syndrome (A CS) is a leading health burden worldwide. The Siriraj non-ST-segment elevation acute coronary syndrome (NST E-A CS) registry was established in 2012. Here, we report in-hospital outcomes and one-year outcomes from patients in the registry.

OBJECTIVE: To investigate and report characteristics and outcomes of treatment for NSTE-ACS at one year from a single center

MATERIAL AND METHOD: All patients admitted to Siriraj Hospital with diagnosis of NSTE-ACS were enrolled. Baseline demographic information, presenting signs and symptoms, electrocardiogram, and blood chemistry were recorded. In-hospital complications and outcomes of treatment were also collected and recorded. After being discharged from the hospital, patients were followed-up for one year.

RESULTS: Two-hundred patients were evaluated between January 2012 and August 2013. A majority of patients (65.5%) presented with angina. Median TIMI risk score was 4. Thirty-two percent of patients had GR ACE risk score greater than 140. In-hospital mortality was 3.5% (95% CI 2.0-7.0). The most common complication was heart failure (36.5%). Three patients had CVA during admission. At one year the mortality rate was 5% (95% CI 3.0-9.0). Unplanned readmission rate was 9.5%.

CONCLUSION: Most patients in the registry were high-risk ACS patients. In-hospital mortality and one-year mortality rates were 3.5% and 5%, respectively. Results from this study were comparable to results reported by previous studies from the Western world