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The evaluation of the synergistic effect of 3-(2,4-dihydroxyphenyl)propionic acid and l-ascorbic acid on tyrosinase inhibition.

Xinyang Chen, Aya Haniu, Takehiro Kashiwagi, Hiroyuki Watanabe, Takashi Watanabe, Yoshino Okamoto, Masanobu Suzuki, Chul-Sa Kim
Zeitschrift Für Naturforschung. C, A Journal of Biosciences 2017 March 2
3-(2,4-Dihydroxyphenyl)propionic acid (DDPA) and l-ascorbic acid (vitamin C) show tyrosinase inhibition activity. A synergistic effect on tyrosinase inhibition was observed when the two compounds were mixed. The effect significantly decreased the IC50 value of both compounds.

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